{"id":630,"date":"2026-08-20T17:23:06","date_gmt":"2026-08-20T17:23:06","guid":{"rendered":"https:\/\/medatlashealth.com\/?p=630"},"modified":"2026-10-28T12:15:53","modified_gmt":"2026-10-28T12:15:53","slug":"insulin-resistance-explained","status":"publish","type":"post","link":"https:\/\/medatlashealth.com\/sr\/insulin-resistance-explained\/","title":{"rendered":"Insulinska rezistencija: \u0160ta se de\u0161ava u va\u0161em organizmu?"},"content":{"rendered":"<div class=\"wp-block-group is-vertical is-content-justification-left is-layout-flex wp-container-core-group-is-layout-df7bfe9b wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Insulinska rezistencija se \u010desto razvija neprimetno. Mo\u017eete se ose\u0107ati potpuno normalno, dok va\u0161 organizam ve\u0107 ula\u017ee dodatni napor kako bi odr\u017eao nivo \u0161e\u0107era u krvi pod kontrolom.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">U sredi\u0161tu ovog procesa nalazi se insulin \u2014 hormon koji poma\u017ee \u0107elijama da koriste glukozu za dobijanje energije i odr\u017eava nivo glukoze u krvi u zdravim granicama.<\/p>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile has-border-color has-background\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:10px;padding-right:10px;padding-bottom:10px;padding-left:10px;grid-template-columns:55% auto\"><figure class=\"wp-block-media-text__media\"><video controls src=\"https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/Glucose_and_insulin_molecules.mp4\"><\/video><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"wp-block-paragraph translation-block\" style=\"padding-top:var(--wp--preset--spacing--40)\">Kada \u0107elije postanu manje osetljive na insulin, pankreas to u po\u010detku nadokna\u0111uje tako \u0161to proizvodi ve\u0107e koli\u010dine ovog hormona. Tokom odre\u0111enog vremena, na taj na\u010din nivo glukoze u krvi mo\u017ee ostati relativno normalan. Me\u0111utim, ako se ovaj proces nastavi, organizam vremenom mo\u017ee imati sve vi\u0161e pote\u0161ko\u0107a da odr\u017eava ravnote\u017eu, \u010dime se pove\u0107ava rizik od predijabetesa, a kasnije i dijabetesa tipa 2.<\/p>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph\">\u0160ta se onda zapravo de\u0161ava u organizmu kada se razvije insulinska rezistencija?<\/p>\n\n\n<style>.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-content-wrap{padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-right:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);padding-left:var(--global-kb-spacing-sm, 1.5rem);background-color:#f4f9ff;border-top:1px solid #cedff2;border-right:1px solid #cedff2;border-bottom:1px solid #cedff2;border-left:1px solid #cedff2;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-right-radius:18px;border-bottom-left-radius:18px;}.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-contents-title-wrap{padding-top:10px;padding-right:12px;padding-bottom:10px;padding-left:12px;}.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-contents-title-wrap{color:#245fb8;}.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-contents-title{color:#245fb8;font-size:20px;font-weight:regular;font-style:normal;}.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-content-wrap .kb-table-of-content-list{font-weight:regular;font-style:normal;margin-top:var(--global-kb-spacing-sm, 1.5rem);margin-right:0px;margin-bottom:0px;margin-left:0px;}.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-toggle-icon-style-basiccircle .kb-table-of-contents-icon-trigger:after, .kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-toggle-icon-style-basiccircle .kb-table-of-contents-icon-trigger:before, .kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-toggle-icon-style-arrowcircle .kb-table-of-contents-icon-trigger:after, .kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-toggle-icon-style-arrowcircle .kb-table-of-contents-icon-trigger:before, .kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-toggle-icon-style-xclosecircle .kb-table-of-contents-icon-trigger:after, .kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-toggle-icon-style-xclosecircle .kb-table-of-contents-icon-trigger:before{background-color:#f4f9ff;}@media all and (max-width: 1024px){.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-content-wrap{border-top:1px solid #cedff2;border-right:1px solid #cedff2;border-bottom:1px solid #cedff2;border-left:1px solid #cedff2;}}@media all and (max-width: 767px){.kb-table-of-content-nav.kb-table-of-content-id630_cd8fcc-29 .kb-table-of-content-wrap{border-top:1px solid #cedff2;border-right:1px solid #cedff2;border-bottom:1px solid #cedff2;border-left:1px solid #cedff2;}}<\/style>\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_fd8766-f3 .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_fd8766-f3{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_fd8766-f3 alignnone\"><style>.kt-svg-item-630_ca0b5d-69 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_ca0b5d-69 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_ca0b5d-69\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-1\" style=\"border-top-left-radius:222px;border-top-right-radius:222px;border-bottom-left-radius:222px;border-bottom-right-radius:222px;color:#245fb8\"><strong>\u0160ta je insulinska rezistencija?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph translation-block\">Insulinska rezistencija je stanje u kojem \u0107elije u tkivima kao \u0161to su skeletni mi\u0161i\u0107i, masno tkivo i jetra ne reaguju na insulin onoliko efikasno koliko bi trebalo. Insulin mo\u017eemo posmatrati kao metaboli\u010dki signal.<\/p>\n\n\n\n<p class=\"has-text-align-left wp-block-paragraph translation-block\">Nakon \u0161to unesete ugljene hidrate, tokom varenja mnogi od njih se razgra\u0111uju do glukoze. Glukoza zatim ulazi u krvotok, zbog \u010dega raste njen nivo u krvi. Kao odgovor na to, specijalizovane beta \u0107elije pankreasa osloba\u0111aju insulin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Insulin zatim \u0161alje signal razli\u010ditim tkivima kako da iskoriste i skladi\u0161te pristiglu energiju.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kada je osetljivost na insulin normalna, ovaj sistem funkcioni\u0161e efikasno. Kada se razvije insulinska rezistencija, potreban je sna\u017eniji insulinski signal da bi se postigao sli\u010dan efekat.<\/p>\n\n\n\n<p class=\"has-text-align-center wp-block-paragraph translation-block\">Pankreas na to \u010desto odgovara stvaranjem dodatnih koli\u010dina insulina \u2014 kompenzatornim stanjem poznatim kao hiperinsulinemija.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_77a9a0-c8 .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_77a9a0-c8{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_77a9a0-c8 alignnone\"><style>.kt-svg-item-630_040c80-8b .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_040c80-8b .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_040c80-8b\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-2\" style=\"border-top-left-radius:199px;border-top-right-radius:199px;border-bottom-left-radius:199px;border-bottom-right-radius:199px;color:#245fb8\"><strong>Koja je normalna uloga insulina?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Insulin ima mnogo \u0161iru ulogu od jednostavnog \u201esni\u017eavanja \u0161e\u0107era u krvi\u201c.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Nakon obroka, porast nivoa glukoze u krvi podsti\u010de pankreas da osloba\u0111a insulin. Insulin zatim koordinira na\u010din na koji organizam koristi i skladi\u0161ti hranljive materije.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-3\" style=\"color:#1e73be\">Skeletni mi\u0161i\u0107i<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Skeletni mi\u0161i\u0107i predstavljaju jedno od va\u017enih mesta za preuzimanje glukoze nakon obroka.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Insulin se vezuje za receptore na mi\u0161i\u0107nim \u0107elijama i aktivira signalne procese unutar \u0107elije. Jedan od rezultata je pomeranje GLUT4 transportera glukoze prema \u0107elijskoj membrani.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ovi transporteri omogu\u0107avaju da ve\u0107a koli\u010dina glukoze u\u0111e u mi\u0161i\u0107nu \u0107eliju, gde mo\u017ee biti iskori\u0161\u0107ena za dobijanje energije ili uskladi\u0161tena u obliku glikogena.<\/p>\n\n\n<style>.kb-image630_f20a58-99 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image630_f20a58-99 size-large\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/Glut4-receptor-1024x683.png\" alt=\"\" class=\"kb-img wp-image-636\" srcset=\"https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/Glut4-receptor-1024x683.png 1024w, https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/Glut4-receptor-300x200.png 300w, https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/Glut4-receptor-768x512.png 768w, https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/Glut4-receptor.png 1536w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><figcaption><strong>Insulin se vezuje za receptore na povr\u0161ini \u0107elije, pokre\u0107u\u0107i signalne procese unutar \u0107elije koji pomeraju GLUT4 transportere prema \u0107elijskoj membrani i omogu\u0107avaju ulazak glukoze u \u0107eliju.<\/strong><\/figcaption><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-4\" style=\"color:#1e73be\">Jetra<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Jetra ima va\u017enu ulogu u regulaciji nivoa glukoze u krvi.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kada nivo insulina poraste nakon obroka, insulin normalno daje signal jetri da smanji sopstvenu proizvodnju glukoze, istovremeno podsti\u010du\u0107i skladi\u0161tenje energije.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-5\" style=\"color:#1e73be\">Masno tkivo<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Insulin tako\u0111e uti\u010de na masno tkivo. Podsti\u010de skladi\u0161tenje energije i smanjuje razgradnju uskladi\u0161tenih masti kada organizam ima dovoljno dostupne energije.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zajedno, ovi procesi poma\u017eu u spre\u010davanju zadr\u017eavanja prevelike koli\u010dine glukoze u krvotoku.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_536b1b-31 .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_536b1b-31{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_536b1b-31 alignnone\"><style>.kt-svg-item-630_2ae2b5-d1 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_2ae2b5-d1 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_2ae2b5-d1\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-6\" style=\"border-top-left-radius:170px;border-top-right-radius:170px;border-bottom-left-radius:170px;border-bottom-right-radius:170px;color:#245fb8\"><strong>\u0160ta se de\u0161ava kod insulinske rezistencije?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Insulinska rezistencija ne zna\u010di da je insulin potpuno prestao da deluje.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Umesto toga, tkiva postaju manje osetljiva na njegov signal.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zamislite da insulin \u0161alje poruku mi\u0161i\u0107noj \u0107eliji:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u201eGlukoza je dostupna. Preuzmi je.\u201c<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">Kod \u0107elije koja je osetljiva na insulin, ova poruka izaziva sna\u017ean odgovor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kod \u0107elije koja je rezistentna na insulin, ista koli\u010dina insulina izaziva slabiji odgovor.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zbog toga pankreas mora da po\u0161alje sna\u017eniji signal osloba\u0111anjem ve\u0107e koli\u010dine insulina.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tako nastaje va\u017ean niz metaboli\u010dkih promena.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h6 class=\"wp-block-heading\">Faza 1 \u2014 Smanjena osetljivost na insulin<\/h6>\n\n\n\n<p class=\"wp-block-paragraph\">Mi\u0161i\u0107no, masno i tkivo jetre postaju manje osetljivi na insulin.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h6 class=\"wp-block-heading\">Faza 2 \u2014 Pankreas nadokna\u0111uje smanjenu osetljivost<\/h6>\n\n\n\n<p class=\"wp-block-paragraph\">Beta \u0107elije pankreasa pove\u0107avaju lu\u010denje insulina.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Nivo glukoze u krvi i dalje mo\u017ee ostati u normalnim granicama jer ve\u0107a koncentracija insulina nadokna\u0111uje smanjenu osetljivost tkiva na njegovo delovanje.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">To je jedan od razloga zbog kojih insulinska rezistencija mo\u017ee postojati pre nego \u0161to rutinske analize glukoze u krvi poka\u017eu abnormalne vrednosti.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h6 class=\"wp-block-heading\">Faza 3 \u2014 Regulacija glukoze postaje ote\u017eana<\/h6>\n\n\n\n<p class=\"wp-block-paragraph\">Ako insulinska rezistencija napreduje, pankreas vremenom mo\u017eda vi\u0161e ne\u0107e mo\u0107i u dovoljnoj meri da nadoknadi smanjenu osetljivost tkiva na insulin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Nivo glukoze u krvi po\u010dinje da raste.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<div class=\"wp-block-group has-border-color\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-71739e78 wp-block-group-is-layout-constrained\">\n<h6 class=\"wp-block-heading\">Faza 4 \u2014 Predijabetes i dijabetes tipa 2<\/h6>\n\n\n\n<p class=\"wp-block-paragraph\">Trajno pogor\u0161anje regulacije glukoze mo\u017ee dovesti do predijabetesa, a kod nekih osoba i do dijabetesa tipa 2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ne\u0107e svaka osoba sa insulinskom rezistencijom razviti dijabetes i napredovanje bolesti nije neizbe\u017eno.<\/p>\n<\/div><\/div>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/insulin-resist-1024x683.png\" alt=\"\" class=\"wp-image-633\" srcset=\"https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/insulin-resist-1024x683.png 1024w, https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/insulin-resist-300x200.png 300w, https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/insulin-resist-768x512.png 768w, https:\/\/medatlashealth.com\/wp-content\/uploads\/2026\/08\/insulin-resist.png 1536w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_98e023-32 .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_98e023-32{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_98e023-32 alignnone\"><style>.kt-svg-item-630_a1477b-c2 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_a1477b-c2 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_a1477b-c2\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-7\" style=\"border-top-left-radius:222px;border-top-right-radius:222px;border-bottom-left-radius:222px;border-bottom-right-radius:222px;color:#245fb8\"><strong>Insulinska rezistencija u razli\u010ditim organima<\/strong><\/h2>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Insulinska rezistencija na razli\u010dite na\u010dine uti\u010de na vi\u0161e tkiva u organizmu.<\/p>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<h4 class=\"wp-block-heading has-text-align-left has-text-color has-link-color wp-elements-8\" style=\"color:#1e73be\">Mi\u0161i\u0107i: Manje efikasno preuzimanje glukoze<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Skeletni mi\u0161i\u0107i nakon obroka normalno preuzimaju zna\u010dajnu koli\u010dinu glukoze iz krvotoka.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kada mi\u0161i\u0107i postanu rezistentni na insulin, preuzimanje glukoze pod dejstvom insulina postaje manje efikasno.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zbog toga nivo glukoze u krvi nakon obroka mo\u017ee du\u017ee ostati povi\u0161en.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-9\" style=\"color:#1e73be\">Jetra: Proizvodnja glukoze u pogre\u0161no vreme<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Jedna od normalnih uloga insulina jeste da signalizira jetri da u krvotoku ve\u0107 postoji dovoljno glukoze.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kod insulinske rezistencije jetre ovaj signal postaje manje efikasan.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Jetra mo\u017ee nastaviti da osloba\u0111a glukozu \u010dak i kada su nivoi glukoze i insulina u krvi ve\u0107 povi\u0161eni.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Ovakva neadekvatna proizvodnja glukoze u jetri posebno je va\u017ena za razvoj povi\u0161enog nivoa glukoze u krvi nata\u0161te.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-10\" style=\"color:#1e73be\">Masno tkivo: Promenjen metabolizam masti<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Insulin normalno smanjuje osloba\u0111anje masnih kiselina iz uskladi\u0161tenih telesnih masti.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kod insulinske rezistencije ova regulacija postaje manje efikasna. Pove\u0107ana koli\u010dina masnih kiselina u cirkulaciji mo\u017ee uticati na metaboli\u010dke procese u jetri i mi\u0161i\u0107ima i dodatno doprineti insulinskoj rezistenciji.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ovo poma\u017ee da razumemo za\u0161to insulinska rezistencija nije samo \u201eproblem sa \u0161e\u0107erom u krvi\u201c. Ona uklju\u010duje \u010ditavu mre\u017eu promena u metabolizmu glukoze i masti.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_203d6e-1f .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_203d6e-1f{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_203d6e-1f alignnone\"><style>.kt-svg-item-630_d25c0c-5a .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_d25c0c-5a .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_d25c0c-5a\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-11\" style=\"border-top-left-radius:199px;border-top-right-radius:199px;border-bottom-left-radius:199px;border-bottom-right-radius:199px;color:#245fb8\"><strong>\u0160ta uzrokuje insulinsku rezistenciju?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Ne postoji jedan jedini uzrok.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Insulinska rezistencija nastaje kao rezultat slo\u017eenog me\u0111usobnog delovanja genetike, telesnog sastava, fizi\u010dke aktivnosti, hormona, lekova, starenja, sna i drugih zdravstvenih stanja.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<p class=\"wp-block-paragraph\">Va\u017eni faktori rizika uklju\u010duju:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Prekomernu telesnu masu ili gojaznost, naro\u010dito vi\u0161ak masnog tkiva u predelu stomaka i visceralne masti<\/li>\n\n\n\n<li>Fizi\u010dku neaktivnost<\/li>\n\n\n\n<li>Porodi\u010dnu anamnezu dijabetesa tipa 2<\/li>\n\n\n\n<li>Starije \u017eivotno doba<\/li>\n\n\n\n<li>Sindrom policisti\u010dnih jajnika (PCOS)<\/li>\n\n\n\n<li>Gestacijski dijabetes u anamnezi<\/li>\n\n\n\n<li>Apneju u snu<\/li>\n\n\n\n<li>Odre\u0111ene endokrine poreme\u0107aje<\/li>\n\n\n\n<li>Odre\u0111ene lekove, uklju\u010duju\u0107i dugotrajnu terapiju glukokortikoidima i pojedine antipsihotike<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Me\u0111utim, insulinska rezistencija mo\u017ee se javiti i kod osoba koje nemaju gojaznost.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Zbog toga se samo na osnovu izgleda ili telesne mase ne mo\u017ee utvrditi da li osoba ima insulinsku rezistenciju.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_a64a90-d8 .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_a64a90-d8{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_a64a90-d8 alignnone\"><style>.kt-svg-item-630_941286-80 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_941286-80 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_941286-80\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-12\" style=\"border-top-left-radius:206px;border-top-right-radius:206px;border-bottom-left-radius:206px;border-bottom-right-radius:206px;color:#245fb8\"><strong>Da li insulinska rezistencija izaziva simptome?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph translation-block\">\u010cesto nema o\u010diglednih simptoma.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Osoba mo\u017ee godinama imati insulinsku rezistenciju, a da toga nije svesna.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-9eef0109 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<p class=\"wp-block-paragraph\">Kod nekih osoba mogu se razviti stanja ili fizi\u010dki znaci povezani sa insulinskom rezistencijom, kao \u0161to su:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Predijabetes<\/li>\n\n\n\n<li>Povi\u0161eni trigliceridi<\/li>\n\n\n\n<li>Nizak HDL holesterol<\/li>\n\n\n\n<li>Povi\u0161en krvni pritisak<\/li>\n\n\n\n<li>Metaboli\u010dka disfunkcija povezana sa steatoti\u010dnom bole\u0161\u0107u jetre (MASLD)<\/li>\n\n\n\n<li>Sindrom policisti\u010dnih jajnika<\/li>\n\n\n\n<li>- Acanthosis nigricans \u2014 podru\u010dja tamnije i zadebljale ko\u017ee, \u010desto na vratu ili u ko\u017enim pregibima<\/li>\n<\/ul>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Simptomi kao \u0161to su poja\u010dana \u017ee\u0111, u\u010destalo mokrenje, umor ili neobja\u0161njiv gubitak telesne mase vi\u0161e ukazuju na zna\u010dajnu hiperglikemiju ili dijabetes nego \u0161to predstavljaju pouzdane rane pokazatelje same insulinske rezistencije.<\/p>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_a11e82-6b .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_a11e82-6b{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_a11e82-6b alignnone\"><style>.kt-svg-item-630_c7b9cd-c7 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_c7b9cd-c7 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_c7b9cd-c7\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-13\" style=\"border-top-left-radius:180px;border-top-right-radius:180px;border-bottom-left-radius:180px;border-bottom-right-radius:180px;color:#245fb8\"><strong>Kako se dijagnostikuje insulinska rezistencija?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Va\u017eno je napraviti razliku:<\/p>\n\n\n\n<p class=\"has-border-color has-background wp-block-paragraph\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><strong>Ne postoji jedan rutinski klini\u010dki test krvi kojim se direktno dijagnostikuje insulinska rezistencija na isti na\u010din na koji se standardnim testovima dijagnostikuju predijabetes ili dijabetes.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Postoje veoma precizne metode za merenje osetljivosti na insulin, ali se neke od njih prvenstveno koriste u istra\u017eivanjima.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">U svakodnevnoj klini\u010dkoj praksi zdravstveni radnici obi\u010dno procenjuju kombinaciju faktora rizika, fizi\u010dkih znakova i laboratorijskih rezultata.<\/p>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Uobi\u010dajeni testovi za procenu regulacije glukoze uklju\u010duju:<\/p>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-14\" style=\"color:#1e73be\">Glukoza u plazmi nata\u0161te<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Ovim testom meri se nivo glukoze u krvi nakon perioda gladovanja.<\/p>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Za osobe koje nisu trudne:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li class=\"translation-block\">Normalno: ispod 100 mg\/dL (5,6 mmol\/L)<\/li>\n\n\n\n<li class=\"translation-block\">Predijabetes: 100\u2013125 mg\/dL (5,6\u20136,9 mmol\/L)<\/li>\n\n\n\n<li class=\"translation-block\">- Dijabetes: 126 mg\/dL (7,0 mmol\/L) ili vi\u0161e*<\/li>\n<\/ul>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-15\" style=\"color:#1e73be\">HbA1c<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">HbA1c daje procenu prose\u010dne izlo\u017eenosti povi\u0161enim vrednostima glukoze u krvi tokom pribli\u017eno prethodna tri meseca.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li class=\"translation-block\">Normalno: ispod 5,7%<\/li>\n\n\n\n<li><strong>Prediabetes:<\/strong> 5.7\u20136.4%<\/li>\n\n\n\n<li class=\"translation-block\">- Dijabetes: 6,5% ili vi\u0161e*<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-16\" style=\"color:#1e73be\">Oralni test tolerancije na glukozu (OGTT)<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Dva sata nakon oralnog unosa 75 grama glukoze:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li class=\"translation-block\">Normalno: ispod 140 mg\/dL (7,8 mmol\/L)<\/li>\n\n\n\n<li class=\"translation-block\">Predijabetes: 140\u2013199 mg\/dL (7,8\u201311,0 mmol\/L)<\/li>\n\n\n\n<li class=\"translation-block\">Dijabetes: 200 mg\/dL (11,1 mmol\/L) ili vi\u0161e*<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">*Ako nema jasnih znakova hiperglikemije, abnormalne rezultate koji se koriste za postavljanje dijagnoze dijabetesa uglavnom je potrebno potvrditi ponovljenim testiranjem.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Lekari mogu proceniti i nivo lipida u krvi, krvni pritisak, obim struka, zdravlje jetre i druge metaboli\u010dke faktore rizika, u zavisnosti od pojedinca.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_a2e70e-ab .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_a2e70e-ab{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_a2e70e-ab alignnone\"><style>.kt-svg-item-630_07596a-c4 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_07596a-c4 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_07596a-c4\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-17\" style=\"border-top-left-radius:199px;border-top-right-radius:199px;border-bottom-left-radius:199px;border-bottom-right-radius:199px;color:#245fb8\"><strong>Mo\u017ee li se insulinska rezistencija pobolj\u0161ati?<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph translation-block\">Kod mnogih ljudi osetljivost na insulin mo\u017ee se zna\u010dajno pobolj\u0161ati.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Najefikasniji pristup zavisi od faktora koji doprinose razvoju insulinske rezistencije.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group\" style=\"margin-top:0;margin-bottom:0\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-align-left has-text-color has-link-color wp-elements-18\" style=\"color:#1e73be\">Fizi\u010dka aktivnost<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Ve\u017ebanje predstavlja jedan od najefikasnijih na\u010dina za pobolj\u0161anje metaboli\u010dkog zdravlja.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kontrakcije mi\u0161i\u0107a mogu pove\u0107ati preuzimanje glukoze, dok redovna fizi\u010dka aktivnost vremenom pobolj\u0161ava odgovor organizma na insulin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">I aerobna fizi\u010dka aktivnost i trening sa optere\u0107enjem mogu biti korisni.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-19\" style=\"color:#1e73be\">Kontrola telesne mase<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Kod osoba sa prekomernom telesnom masom ili gojazno\u0161\u0107u, \u010dak i umeren gubitak telesne mase mo\u017ee dovesti do zna\u010dajnog pobolj\u0161anja metaboli\u010dkog zdravlja.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Velika studija Diabetes Prevention Program pokazala je da je kod osoba sa visokim rizikom od razvoja dijabetesa tipa 2 promena \u017eivotnih navika koja je uklju\u010divala gubitak pribli\u017eno 5\u20137% telesne mase zna\u010dajno smanjila napredovanje ka dijabetesu.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-20\" style=\"color:#1e73be\">Ishrana<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Ne postoji jedna \u201edijeta za insulinsku rezistenciju\u201c koja odgovara svima.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Odr\u017eiv na\u010din ishrane uglavnom treba da uklju\u010duje:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Povr\u0107e<\/li>\n\n\n\n<li>Celovito vo\u0107e<\/li>\n\n\n\n<li>Integralne \u017eitarice i druge izvore ugljenih hidrata bogate vlaknima<\/li>\n\n\n\n<li>Mahunarke<\/li>\n\n\n\n<li>Odgovaraju\u0107e izvore proteina<\/li>\n\n\n\n<li>Nezasi\u0107ene masti<\/li>\n\n\n\n<li>Minimalno prera\u0111ene namirnice<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Smanjenje \u010deste konzumacije napitaka zasla\u0111enih \u0161e\u0107erom i visoko prera\u0111enih, energetski bogatih namirnica tako\u0111e mo\u017ee doprineti boljem metaboli\u010dkom zdravlju.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Celokupan na\u010din ishrane va\u017eniji je od ozna\u010davanja pojedina\u010dnih namirnica kao \u201edobrih\u201c ili \u201elo\u0161ih\u201c.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-8bd6105a wp-block-group-is-layout-flex\" style=\"border-color:#1e73be;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\">\n<h4 class=\"wp-block-heading has-text-color has-link-color wp-elements-21\" style=\"color:#1e73be\">San<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Dovoljno kvalitetnog i redovnog sna predstavlja jo\u0161 jedan va\u017ean deo metaboli\u010dkog zdravlja.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Poreme\u0107aji spavanja, kao \u0161to je opstruktivna apneja u snu, povezani su sa insulinskom rezistencijom, zbog \u010dega su odgovaraju\u0107a procena i le\u010denje va\u017eni kada za to postoje medicinske indikacije.<\/p>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-55cc8e6c wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;margin-top:var(--wp--preset--spacing--50);padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_2639c9-8c .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_2639c9-8c{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_2639c9-8c alignnone\"><style>.kt-svg-item-630_407820-de .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_407820-de .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_407820-de\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-22\" style=\"border-top-left-radius:180px;border-top-right-radius:180px;border-bottom-left-radius:180px;border-bottom-right-radius:180px;color:#245fb8\"><strong>Insulinska rezistencija i predijabetes<\/strong><\/h2>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Ovi pojmovi su povezani, ali nisu isto.<\/p>\n\n\n\n<div class=\"wp-block-group has-border-color has-background\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#d3e4f8;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-71739e78 wp-block-group-is-layout-constrained\">\n<p class=\"wp-block-paragraph translation-block\">Insulinska rezistencija ozna\u010dava smanjenu biolo\u0161ku osetljivost na insulin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Predijabetes se defini\u0161e vrednostima glukoze u krvi ili HbA1c koje su iznad normalnog opsega, ali ispod dijagnosti\u010dkog praga za dijabetes.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Osoba zato mo\u017ee imati insulinsku rezistenciju dok nivo glukoze u krvi i dalje ostaje normalan, jer pankreas jo\u0161 uvek proizvodi dovoljno dodatnog insulina da nadoknadi smanjenu osetljivost tkiva.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Predijabetes se mo\u017ee razviti kasnije, kada ova kompenzacija vi\u0161e nije dovoljna.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-content-justification-center is-nowrap is-layout-flex wp-container-core-group-is-layout-930d7113 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_6e8696-01 .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_6e8696-01{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_6e8696-01 alignnone\"><style>.kt-svg-item-630_c06471-e9 .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_c06471-e9 .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_c06471-e9\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-23\" style=\"border-top-left-radius:225px;border-top-right-radius:225px;border-bottom-left-radius:225px;border-bottom-right-radius:225px;color:#245fb8\"><strong>\u0160ira slika<\/strong><\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-4fc3f8e1 wp-block-group-is-layout-flex\">\n<p class=\"wp-block-paragraph\">Insulinska rezistencija nije samo posledica unosa prevelike koli\u010dine \u0161e\u0107era.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Ona predstavlja slo\u017eenu promenu u na\u010dinu na koji razli\u010diti organi me\u0111usobno komuniciraju i upravljaju energijom.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mi\u0161i\u0107i postaju manje efikasni u preuzimanju glukoze.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Jetra slabije reaguje na signal insulina da smanji proizvodnju glukoze.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Metabolizam masti se menja.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pankreas odgovara proizvodnjom ve\u0107e koli\u010dine insulina.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tokom odre\u0111enog vremena ova kompenzacija mo\u017ee funkcionisati izuzetno dobro.<\/p>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Me\u0111utim, kada organizam vi\u0161e ne mo\u017ee da odr\u017eava normalnu regulaciju glukoze, njen nivo u krvi po\u010dinje da raste \u2014 stvaraju\u0107i metaboli\u010dke uslove u kojima stanje mo\u017ee napredovati od insulinske rezistencije preko predijabetesa do dijabetesa tipa 2.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Va\u017eno je da ovakvo napredovanje nije neizbe\u017eno. Fizi\u010dka aktivnost, odgovaraju\u0107a ishrana, kvalitetan san, kontrola telesne mase kada je potrebna i odgovaraju\u0107e medicinsko le\u010denje mogu zna\u010dajno pobolj\u0161ati metaboli\u010dko zdravlje i smanjiti rizik od razvoja dijabetesa tipa 2.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-border-color has-background\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#f4f9ff;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-71739e78 wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-group medatlas-h2 has-border-color has-background is-nowrap is-layout-flex wp-container-core-group-is-layout-75b05be6 wp-block-group-is-layout-flex\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;background-color:#eaf2fb;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><style>.kt-svg-icons630_9e6f42-4d .kt-svg-item-0 .kb-svg-icon-wrap{color:var(--global-palette4, #2D3748);font-size:50px;}.wp-block-kadence-icon.kt-svg-icons630_9e6f42-4d{justify-content:center;}<\/style>\n<div class=\"wp-block-kadence-icon kt-svg-icons kt-svg-icons630_9e6f42-4d alignnone\"><style>.kt-svg-item-630_2d7823-bc .kb-svg-icon-wrap, .kt-svg-style-stacked.kt-svg-item-630_2d7823-bc .kb-svg-icon-wrap{color:#1167d8;font-size:40px;}<\/style>\n<div class=\"wp-block-kadence-single-icon kt-svg-style-default kt-svg-icon-wrap kt-svg-item-630_2d7823-bc\"><span class=\"kb-svg-icon-wrap kb-svg-icon-fas_capsules\"><svg viewbox=\"0 0 576 512\"  fill=\"currentColor\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"  aria-hidden=\"true\"><path d=\"M555.3 300.1L424.2 112.8C401.9 81 366.4 64 330.4 64c-22.6 0-45.5 6.7-65.5 20.7-19.7 13.8-33.7 32.8-41.5 53.8C220.5 79.2 172 32 112 32 50.1 32 0 82.1 0 144v224c0 61.9 50.1 112 112 112s112-50.1 112-112V218.9c3.3 8.6 7.3 17.1 12.8 25L368 431.2c22.2 31.8 57.7 48.8 93.8 48.8 22.7 0 45.5-6.7 65.5-20.7 51.7-36.2 64.2-107.5 28-159.2zM160 256H64V144c0-26.5 21.5-48 48-48s48 21.5 48 48v112zm194.8 44.9l-65.6-93.7c-7.7-11-10.7-24.4-8.3-37.6 2.3-13.2 9.7-24.8 20.7-32.5 8.5-6 18.5-9.1 28.8-9.1 16.5 0 31.9 8 41.3 21.5l65.6 93.7-82.5 57.7z\"\/><\/svg><\/span><\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color wp-elements-24\" style=\"border-top-left-radius:248px;border-top-right-radius:248px;border-bottom-left-radius:248px;border-bottom-right-radius:248px;color:#245fb8\"><strong>\u010cesto postavljana pitanja<\/strong><\/h2>\n<\/div>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Mo\u017eete li imati insulinsku rezistenciju uz normalan nivo \u0161e\u0107era u krvi?<\/summary>\n<p class=\"has-border-color has-theme-palette-9-background-color has-background wp-block-paragraph\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:10px;padding-right:10px;padding-bottom:10px;padding-left:10px\">Da. U ranoj fazi pankreas mo\u017ee nadoknaditi smanjenu osetljivost na insulin tako \u0161to proizvodi ve\u0107e koli\u010dine ovog hormona, omogu\u0107avaju\u0107i da nivo glukoze u krvi ostane u normalnim granicama.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Da li insulinska rezistencija uvek prelazi u dijabetes?<\/summary>\n<p class=\"has-border-color has-theme-palette-9-background-color has-background wp-block-paragraph\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:10px;padding-right:10px;padding-bottom:10px;padding-left:10px\">Ne. Insulinska rezistencija pove\u0107ava rizik od razvoja dijabetesa tipa 2, ali napredovanje nije neizbe\u017eno. Promene \u017eivotnih navika i, kada je potrebno, odgovaraju\u0107e medicinsko le\u010denje mogu zna\u010dajno smanjiti taj rizik.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Mogu li mr\u0161ave osobe imati insulinsku rezistenciju?<\/summary>\n<p class=\"has-border-color has-theme-palette-9-background-color has-background wp-block-paragraph\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:10px;padding-right:10px;padding-bottom:10px;padding-left:10px\">Da. Iako su vi\u0161ak visceralne masti i gojaznost va\u017eni faktori rizika, insulinska rezistencija mo\u017ee se javiti i kod osoba koje nemaju gojaznost. Genetika, fizi\u010dka aktivnost, odre\u0111eni lekovi, hormonski poreme\u0107aji, raspored masnog tkiva u organizmu i drugi faktori tako\u0111e uti\u010du na osetljivost na insulin.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Da li su insulinska rezistencija i dijabetes isto?<\/summary>\n<p class=\"has-border-color has-theme-palette-9-background-color has-background wp-block-paragraph\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:10px;padding-right:10px;padding-bottom:10px;padding-left:10px\">Ne. Insulinska rezistencija je metaboli\u010dko stanje. Dijabetes se dijagnostikuje kada nivo glukoze u krvi ili HbA1c dostigne utvr\u0111ene dijagnosti\u010dke vrednosti.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary>Mo\u017ee li ve\u017ebanje pobolj\u0161ati osetljivost na insulin?<\/summary>\n<p class=\"has-border-color has-theme-palette-9-background-color has-background wp-block-paragraph\" style=\"border-color:#cedff2;border-width:1px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:10px;padding-right:10px;padding-bottom:10px;padding-left:10px\">Da. Redovna fizi\u010dka aktivnost mo\u017ee pobolj\u0161ati preuzimanje glukoze u skeletnim mi\u0161i\u0107ima i pove\u0107ati osetljivost na insulin. I aerobno ve\u017ebanje i trening sa optere\u0107enjem mogu doprineti boljem metaboli\u010dkom zdravlju.<\/p>\n<\/details>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group has-border-color\" style=\"border-color:#cedff2;border-width:2px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-71739e78 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-align-center\">Medicinska napomena<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ovaj \u010dlanak je namenjen isklju\u010divo u edukativne svrhe i ne predstavlja zamenu za stru\u010dni medicinski savet, dijagnozu ili le\u010denje. Ako ste zabrinuti zbog nivoa glukoze u krvi, insulinske rezistencije, predijabetesa ili rizika od razvoja dijabetesa, obratite se kvalifikovanom zdravstvenom radniku.<\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-group has-border-color\" style=\"border-color:#cedff2;border-width:2px;border-top-left-radius:18px;border-top-right-radius:18px;border-bottom-left-radius:18px;border-bottom-right-radius:18px;padding-top:12px;padding-right:12px;padding-bottom:12px;padding-left:12px\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-container-core-group-is-layout-71739e78 wp-block-group-is-layout-constrained\">\n<h3 class=\"wp-block-heading has-text-align-center\">Medicinski izvori<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>American Diabetes Association. <em>Standards of Care in Diabetes\u20142026: Diagnosis and Classification of Diabetes.<\/em><\/li>\n\n\n\n<li>National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). <em>Insulin Resistance &amp; Prediabetes.<\/em><\/li>\n\n\n\n<li>National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). <em>Diabetes &amp; Prediabetes Tests.<\/em><\/li>\n\n\n\n<li>Endotext, NCBI Bookshelf. <em>Pathogenesis of Type 2 Diabetes Mellitus.<\/em><\/li>\n\n\n\n<li>Endotext, NCBI Bookshelf. <em>Assessing Insulin Sensitivity and Resistance in Humans.<\/em><\/li>\n\n\n\n<li>Diabetes Prevention Program (DPP), National Institutes of Health \/ NIDDK.<\/li>\n<\/ul>\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Saznajte \u0161ta je insulinska rezistencija, kako uti\u010de na nivo \u0161e\u0107era i insulina u krvi, za\u0161to se mo\u017ee razviti i kako mo\u017ee napredovati ka predijabetesu i dijabetesu tipa 2.<\/p>","protected":false},"author":1,"featured_media":631,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[19],"tags":[69,74,70,68,73,71,72],"class_list":["post-630","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-conditions","tag-blood-sugar","tag-glucose-metabolism","tag-insulin","tag-insulin-resistance","tag-metabolic-health","tag-prediabetes","tag-type-2-diabetes"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Insulin Resistance Explained:                What Happens Inside Your Body? 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